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BackgroundOn the African continent, many people live in conditions of adversity known to be associated with the onset of mental disorders, yet not all develop a mental disorder.The prevalence of common mental disorders such as depression and anxiety in the general population of Nigeria is comparatively low.Prevalence data of mental disorders in slu
Mucopolysaccharidosis type IVA (MPS IVA) is a rare genetic disease caused by mutations in the GALNS gene and is inherited in an autosomal recessive manner.GALNS encodes N-acetylgalactosamine-6-sulfatase that breaks down certain read more complex carbohydrates known as glycosaminoglycans (GAGs).Deficiency in this enzyme causes accumulation of GAGs i
In recent years, the development of smart drug delivery systems based on biodegradable polymeric nanoparticles has become of great interest.Drug-loaded nanoparticles can be introduced into the cell interior via endocytotic processes getpureroutine.com followed by the slow release of the drug due to degradation of the nanoparticle.In this work, poly